We are illuminating the dark matter of the cancer genome using a new AI approach we have developed called ARTEMIS. This method reveals genome-wide repeat landscapes in cancer and in cell-free DNA, and shows promise for early detection of lung and liver cancers. Congratulations to Akshaya and members of the team on this important advance in our understanding of the cancer genome!

Annapragada AV, Niknafs N, White JR, Bruhm DC, Cherry C, Medina JE, Adleff V, Hruban C, Mathios D, Foda ZH, Phallen J, Scharpf RB, Velculescu VE. Genome-wide repeat landscapes in cancer and cell-free DNA. Science Translational Medicine. 2024 Mar 13;16(738):eadj9283. doi: 10.1126/scitranslmed.adj9283. Epub 2024 Mar 13. PMID: 38478628. Article | Press